Fished to the Edge: How DNA Identification Can Help Fight the Illegal Trade of Threatened Shark Species

Whether your first encounter was peering through the thick glass of an aquarium tank or peeking through your fingers in a darkened theater, there is something about sharks that captures our imagination. These fierce, and sometimes fearsome, creatures have existed in our oceans for over 400 million years, and  survived multiple mass extinction events, including […]

Feminization and Mass Die Offs: The Effects of Climate Change

Say the words “climate change” in a room full of people and you are bound to inspire some passion in the response—and very likely start an argument. There is no question that emotions and opinions run high whenever this topic is introduced. Most often the debate centers around who or what might be causing changes […]

Fluorescence Dye-Based Quantitation: Sensitive and Specific for NGS Applications

This is the third post in a series of blogs on quantitation for NGS applications written by guest blogger Adam Blatter, Product Specialist in Integrated Solutions at Promega. Fluorescent dye-based quantitation uses specially designed DNA binding compounds that intercalate only with double stranded DNA molecules. When excited by a specific wavelength of light, only dye […]

Welcome to the Anthropocene? Only a Retrospective Analysis Will Tell

The 4.54 billion-year history of the earth is divided into many subdivisions: eons, eras, periods, epochs, and ages with each division representing a smaller chunk of geologic time. If you are a parent of a young child and you happen to have viewed several episodes of the children’s educational program Dinosaur Train, you are probably […]

Celebrating Distinguished Scientists and Peer-Reviewed Publications in Promega R&D

“We are a company that is built upon innovation, and R&D is one of the main drivers of that,” says Frank Fan, Director of Biology at Promega. Promega Research and Development is focused on developing reliable tools that address the biggest problems facing life scientists. However, our R&D scientists do much more than just develop […]

What’s New with Promega Resources?

Whether you’re looking to learn about nucleic acid analysis, wondering how to do an ELISA assay, or simply have ten minutes to kill in your day, Promega resources have you covered! We’ve revamped and upgraded our hub of self-service resources so we can provide the most up-to-date scientific support. Here are some highlights of what’s […]

The BTC Institute: Serving Youth Skills and Science for Summer

World Youth Skills Day provides a unique opportunity to emphasize the importance of equipping young people with experiences, skills, and opportunities in the workforce. This celebratory day falls on July 15th and was officially declared by the United Nations General Assembly in 2014. At Promega, we are constantly adhering to invest in the future generations […]

Getting To Know D.O.O.R.S. Scholar Anusha Ray Dey

“I want to make sure that what I think I want to do, truly is what I want to do.” Anusha Ray Dey started working in a research lab as an undergraduate at the University of Wisconsin-Madison because she imagined it would improve her future application to medical school. However, there was one twist she […]

Detecting Disulfide Bond Shuffling in Biologics Using Trypsin Platinum

Biologic therapeutics such as monoclonal antibodies and biosimilars are complex proteins that are susceptible to post-translational modifications (PTMs). These chemical modifications can affect the performance and activity of the biologic, potentially resulting in decreased potency and increased immunogenicity. Such modifications include glycosylation, deamidation, oxidation and disulfide bond shuffling. These PTMs can be signs of protein […]

Run to Remember: A Mouse-Model Study Investigating the Mechanism of Exercise-Induced Neuroprotection

Research in animal models shows physical exercise can induce changes in the brain. In humans, studies also revealed changes in brain physiology and function resulting from physical exercise, including increased hippocampal and cognitive performance (1). Several studies in mice and rats also demonstrated that exercise can improve learning and memory and decrease neuroinflammation in models […]