I’ve always believed that the best science stories don’t just inform — they move us. And in many cases, that’s quite literal.
Whether I’m designing a figure for a new assay or animating a step-by-step protocol, I see motion as a bridge that turns complexity into clarity. When used well, that bridge transforms scientific communication from dense and static into something dynamic, visual and memorable.
And it’s not just me — a graphic designer — saying this. Scholars like Daniel Liddle describe motion as a form of visual rhetoric: a way to persuade, clarify and build trust through movement. Motion isn’t just decoration — it’s meaning made visible.
In this post, I’ll explore why motion matters in scientific communication and how animation makes complex ideas easier to grasp. From turning a protocol into a story that sticks to making technical jargon something you can remember, motion design helps science feel more approachable and a lot more memorable.
Platelets are best known for their role in blood clotting, but they also participate in other biological processes that influence how cells communicate and behave. In research models, scientists have observed that tumor cells can interact with platelets in ways that affect how they move and attach to new environments. A recent study by Morris et al., published in Scientific Reports, explored the molecular details behind these platelet–cell interactions and the role of calcium in regulating them.
The Role of Integrins and Calcium
The study focused on integrins, which are surface proteins that help cells anchor to their surroundings and communicate with the extracellular matrix. Two integrins, αIIbβ3 and αvβ3, are particularly important because they mediate platelet–platelet and platelet–cancer cell binding. Their structure and function depend on divalent cations such as calcium, which stabilize receptor conformation and support ligand binding.
When extracellular calcium levels were manipulated, platelet behavior changed in distinct ways.
The next generation of medicine may not come in a pill or vial — but in a living community of microbes. Scientists at Pharmabiome, a Zurich-based biotechnology company, are leveraging their expertise in microbiome research to create truly “living” therapies.
More Than a Gut Feeling
All around us – and inside –exists an entire universe of microscopic organisms commonly referred to as the microbiome. In fact, our body contains more microbes than human cells, working hand in hand to maintain normal physiology. The most heavily colonized part of our body is our gastrointestinal (GI) tract – our gut – housing thousands of different bacteria, viruses and fungi. Collectively termed ‘gut microbiota’, this complex network of microorganisms helps us digest nutrients, produces essential metabolites, protects us against pathogens, and more.
The diverse species in our GI tract co-exist in a dynamic equilibrium, each fulfilling a defined set of functions and interacting with other species through cross-feeding mechanisms that, together, promote gut health. When this delicate balance is perturbed, be it through dietary changes, antibiotic treatments, or other factors, the effect ripples across the body. Increasing evidence suggests that gut dysbiosis actively contributes to pathological conditions ranging from inflammatory bowel disease (IBD) and obesity to neurological and autoimmune disorders. The good news is, as our understanding of gut ecology evolves, so does the potential to harness and reshape the microbiome to improve health.
Earlier this fall, more than 90 researchers from academia and industry gathered at the Promega Madison campus for the 4th TPD & Induced Proximity Symposium. The event focused on the rapidly advancing field of targeted protein degradation (TPD) and the broader concept of induced proximity—therapeutic strategies that bring two or more proteins into proximity to trigger a specific biological effect.
This 4th year reflected of the symposium a maturing and diversifying field with chemoproteomics and proteomescale mapping redefining what it means to be “druggable,” while AI and high throughput biology are connecting molecular design to cellular function. Yet the mission remains unchanged—using molecular approaches that leverage the cellular machinery to make progress against targets once deemed “undruggable.”
When Dr. Rebecca Miles retired from her 25-year career in pharmaceutical research at Eli Lilly, she refocused her passion for science on a new challenge. Having worked her way from the bench to Senior Director, she knew first-hand the technical skills required to successfully advance genetic medicine programs. Now, she leverages her industry experience and the latest technologies at Taylor University, a liberal arts institution in Indiana known for its strong emphasis on education and practical training for students’ future careers. As a Visiting Assistant Professor of Biology, Dr. Miles trains her students to develop real-world skills and provides them exposure to technologies that impacted her own career. “I wanted to redesign the lab so that students could come out of the semester with some job skills if they wanted to be a technician in a lab,” she explains.
When Dr. Rebecca Miles retired from her 25-year career in pharmaceutical research at Eli Lilly, she refocused her passion for science on a new challenge. Having worked her way from the bench to Senior Director, she knew first-hand the technical skills required to successfully advance genetic medicine programs. Now, she leverages her industry experience and the latest technologies at Taylor University, a liberal arts institution in Indiana known for its strong emphasis on education and practical training for students’ future careers. As a Visiting Assistant Professor of Biology, Dr. Miles trains her students to develop real-world skills and provides them exposure to technologies that impacted her own career. “I wanted to redesign the lab so that students could come out of the semester with some job skills if they wanted to be a technician in a lab,” she explains.
Dr. Rebecca Miles undergraduate class with their MyGlo®
Teaching Students Modern Technologies
Dr. Miles structures her lab courses to incorporate techniques that scientists would routinely use in an industry setting. Students learn cell culture, plating, luminescent assays, and data analysis in ways that mirror the workflows used in biotech and pharmaceutical labs. She encourages her students to analyze their raw data to learn how the calculations work. “I want the students to calculate it in Excel and do it themselves and see the standard deviation,” she says.
Promega’s luciferase reporter assays are an important part of this training. Rather than using Western blots, which can be challenging for students, Dr. Miles took advantage of the ease of Promega’s NF-κB reporter assays to measure transcription factor activity. The results are both intuitive and impactful. “It’s a great way to show that you can actually have a transcription factor increase RNA and you get this lovely luciferase readout,” she explains. Students are quick to notice the advantages too. As Dr. Miles recalls, “They’ll ask, ‘Hey, I want to do that luciferase assay that was so easy.’” And with CellTiter-Glo® Assays, the students can monitor how their experiments affect cell viability, leveraging the data visualizations that are automatically generated with the ProNect® CellTiter-Glo® app.
Teaching the next generation with MyGlo® and the CellTiter-Glo® app
Making Science Accessible and Engaging
Affordability and portability are major advantages for a teaching institution with limited budgets and space. With a footprint only slightly larger than a microtiter plate, MyGlo® can be stored safely in a drawer and moved easily between teaching labs. “It’s so small, I don’t want it to sprout legs and walk away,” Dr. Miles jokes. The device connects through Wi-Fi, requiring only a power cord, and can be run with ProNect® Data Platform from any computer with internet access. Its user-friendly design means class time is spent on learning science, not troubleshooting equipment.
The integration with the ProNect® Data Platform adds another dimension. Immediately after reads are complete, heat maps are shown, helping students quickly check if their experiments worked before they download raw data for deeper analysis. Dr. Miles appreciates this feature to help the students do a quick QC check of their data. The short read time, color-coded heat maps and exportable data make experiments more interactive while still encouraging students to learn how to properly analyze data.
The experience MyGlo® provides is especially meaningful for undergraduates. Students at Taylor will likely encounter luciferase assays again in graduate school, medical programs, or biotech jobs. By gaining hands-on experience now, they build confidence and familiarity with techniques that will give them an advantage later. “I just felt like training the students on how you can use reporter assays and luciferase-based assays would be critical going forward. It’s just something that they’ll run into,” Dr. Miles explains. She wants them to be familiar with how the assays work, so they’re ready for whatever comes next in their careers.
A Trusted Partner for Scientific Training
MyGlo® has supported Dr. Miles’ vision for training the next generation of scientists. MyGlo® and the ProNect® Data Platform provide the students with sensitivity, accuracy, and user-friendly data visualizations at a price point compatible with limited budgets at teaching institutions. “I was thrilled to be able to access it right at this price point,” she says. “Love the product, love what it can do to teach students.” From her time in industry to her current role, Dr. Miles is focused on mentoring early career scientists and empowering them with knowledge of current technologies for future success. With MyGlo® in the classroom, she continues that mission: one student, one luminescent assay at a time.
Like Dr. Miles, you can bring industry-relevant assays into your classroom. Learn how MyGlo® Reagent Reader and Promega’s luminescent assays could transform your lab courses, and apply for Promega’s Training Support Program.
CellTiter-Glo, ProNect, and MyGlo are registered trademarks of Promega Corporation.
For research use only. Not for use in diagnostic procedures.
Halloween invites us to look beneath the surface—to find the stories hidden in bones, blood, and the echoes of the past. Science, too, has its own way of conjuring the long dead, not through spells but through DNA analysis. The three Promega Connections blogs highlighted below revisit centuries-old mysteries, using modern genetics to reveal the truths hidden where legend once ruled.
The Bones of a King: Richard III
Under a modern car park in Leicester, England, archaeologists uncovered bones twisted by scoliosis and scarred by battle. Could these truly belong to the infamous Richard III? DNA evidence answered with haunting precision in “King Richard III Identified.”
Mitochondrial DNA matched that of a living descendant of Richard’s sister, confirming the king’s identity more than 500 years after his death. Beyond solving a royal mystery, genetic analysis gave historians a clearer picture of the much-maligned monarch—his appearance, stature, and final violent moments. The same technology that identified Richard III may one day reveal the fate of his murdered nephews, the “Princes in the Tower.” Even as bones turn to dust, DNA keeps their stories alive.
Liver disease is a global health challenge, affecting millions each year. The liver has a remarkable ability to regenerate; however, chronic damage arising from obesity, alcohol, or metabolic dysfunction can lead to irreversible failure. At the University of Edinburgh’s Centre for Regenerative Medicine, Professor David Hay’s lab is developing innovative ways to study liver function and disease using a lab-grown mini-organ. In this blog, we highlight how Dr. Hay’s lab is redefining liver disease research through 3D models that reveal how hormones influence metabolic health.
In today’s biotech landscape, speed and precision are essential. For Tridek-One Therapeutics, a Paris-based spin-off from INSERM founded in 2018, these qualities drive their mission to develop first-in-class CD31 checkpoint agonist therapies for autoimmune and inflammatory diseases. By leveraging CD31’s ITIM motifs to modulate ITAM signaling, their approach targets immune cells selectively, reducing the risk of broad immunosuppression.
Operating in a biotech incubator with limited space and shared equipment, the team—including Trang Tran, PhD, Preclinical Research Director, and Guillaume Even, Senior Laboratory Technician—depends on luminescent assays requiring both sensitivity and precise timing. Relying on a shared plate reader often delayed extracellular ATP assays that needed rapid measurement. Walking between lab spaces and potentially waiting for access to the plate reader was not feasible.
Tridek-One needed a dedicated, reliable luminometer that could support their time-sensitive workflow and fit into their small lab space. That’s when Tridek-One discovered the MyGlo® Reagent Reader, Promega’s compact, portable 96-well luminometer and transformed their workflow. Even noted that, when they first tried MyGlo®, they “directly saw the power of this small machine.” Tran and Even found that MyGlo®’s performance and sensitivity were comparable to more expensive multi-mode readers, which gave them confidence in choosing MyGlo® as a reliable and cost-effective solution. Because they prefer to use 96-well microplates, MyGlo® fit their experimental setup perfectly.
Addgene, the nonprofit plasmid-sharing platform trusted by researchers worldwide, and Promega, a global leader in luminescent assay technologies, have joined forces to make your gene expression, pathway analysis, and cell signaling experiments faster, easier, and reproducible.
In this post, we’re spotlighting 5 standout vectors from the new collection that are making life in the lab a whole lot better.
Festival season is here—and apparently, mosquitoes got tickets too.
If you have ever been the person in your friend group who ends a summer concert covered in large, itchy welts while everyone else goes home bite-free, you are not imagining things. Some people really are mosquito magnets.
A new study, aptly titled “Blood, Sweat, and Beers,” set out to uncover what makes certain humans irresistible to mosquitoes. But instead of a sterile lab or a rainforest expedition, this experiment took place at one of the Netherlands’ biggest music festivals; Lowlands, a three-day party with 65,000 attendees, questionable hygiene and plenty of beer. In other words: the perfect breeding ground for this science experiment.
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