One key obstacle to crafting effective gene therapies is the ability to tailor dosing according to a patient’s needs. This can be tricky because even if protein production is successful, staying within the therapeutic window is paramount—too much of a protein could be toxic, and too little will not produce the desired effect. This balance […]
We made the cover! Of Cell Chemical Biology, that is. This July, Cell Chemical Biology editors accepted a study from Promega scientists and invited the research team to submit cover art for the issue. The study in question details a BRET-based method to quantify drug-target occupancy within RAF-KRAS complexes in live cells. Promega scientists Matt Robers and […]
Imagination is often considered a uniquely human trait. Simply put, it is what allows us to think about things that aren’t happening in that moment, and it plays an integral part in our day-to-day lives. We use it when we think through our calendar for the day, consider restaurant options for dinner, or visualize the […]
Model organisms are essential tools in the pursuit of understanding biological processes, elucidating the mechanisms of diseases, and developing potential treatments and therapies. Use of these organisms in scientific research has paved the way for groundbreaking discoveries across various fields of biology. In particular, non-mammalian models can be valuable due to characteristics such as rapid […]
This year ushered in a series of intense weather events that impacted communities across the globe: record-breaking heat waves; super-charged cyclones; intense flooding; coastal waters hitting a balmy 38°C (1–4). Attributing extreme weather to climate change has become the norm when reporting on these seemingly more frequent and intense events. But beyond simply acknowledging weather […]
In the murky depths of the ocean live some of the smartest and most unusual creatures to inhabit the earth. Octopuses are known for their sucker covered tentacles and chameleon-like abilities to change color, pattern and shape to blend it with their environment. The changes aren’t limited to just their appearance. A new study published […]
Some laboratory processes are time-consuming and tedious. Automation highly manual processes such as nucleic acid extraction can increase your lab’s throughput and improve the overall consistency of your results. Unfortunately choosing and implementing one of these systems can seem overwhelming. As you begin to evaluate the automation needs of your lab, one of the first […]
“We are a company that is built upon innovation, and R&D is one of the main drivers of that,” says Frank Fan, Director of Biology at Promega. Promega Research and Development is focused on developing reliable tools that address the biggest problems facing life scientists. However, our R&D scientists do much more than just develop […]
Cells, commonly considered the smallest unit of life, provide structure and function for all living things (3). Because cells contain the fundamental molecules of life, in some situations such as yeast, a single cell can be considered the complete organism. In other situations, for more complex multicellular organisms, a multitude of cells can mature and […]
International Pet Day, observed each year on April 11th, provides the purrfect opportunity to reciprocate all the labored love and affection our pets so freely give us. There’s no doubt that our furry, feathered, and scaley friends greatly improve our quality of life. But did you know there are benefits to this human-animal bond beyond […]
