Supporting CAR-T Cell Therapy with STR Analysis

Engineered T-cell therapies, specifically CAR-T cell therapies, have emerged as a breakthrough treatment for certain types of blood cancers including lymphomas, some forms of leukemia, and most recently, multiple myeloma. CAR (chimeric antigen receptor) T-cell therapy involves collecting T cells from a patient and re-engineering them to detect and destroy cancer cells.

Have No Fear, qPCR Is Here: How qPCR can help identify food contamination

Foodborne disease affects almost 1 in 10 people around the world annually, and continuously presents a serious public health issue (9). More than 200 diseases have evolved from consuming food contaminated by bacteria, viruses, parasites, and chemical substances, resulting in extensive increases in global disease and mortality rates (9). With this, foodborne pathogens cause a […]

D.O.O.R.S. Scholars Day Gives Students a Look Inside Promega

When six undergraduate students from across the country convened at Promega Madison to present their research, several of them were surprised to see Promega CEO Bill Linton in the audience.” “I’ve never interacted with a biotechnology company like this, and then the CEO shows up,” says Valeria Sanchez Estrada. “We actually discussed ChatGPT and how […]

From Biotechnology Youth Apprenticeship to Full-Time Promega Scientist

The Biotechnology Youth Apprenticeship Program hosted by the BTC Institute gives high school students an opportunity to gain hands-on experience in a research lab. Students can work as paid apprentices for either one or two years while also attending weekly training sessions at the BioPharmaceutical Technology Center. Through this program, students can graduate high school […]

The Largest Maxprep Liquid Handler Installation Ever: Kigali Rwanda, 2022

“It was just a sea of Promega everywhere,” says Rebecca Roberts, a Promega Field Applications Scientist. “Floor to ceiling, piled up with Maxwell instruments, Maxprep Liquid Handlers, all the accessories and consumables…” In her role on the Field Application Scientists team, Rebecca travels the United States installing the Maxprep Liquid Handler in customer labs and […]

Shifting Gears: Repurposing Instruments for Changing Needs

The thought of an expensive instrument falling out of use and gathering dust on the shelf is enough to bring a tear to any lab manager’s eye. An instrument that once served a key purpose and now functions only as a “paperweight” is a tragic waste of valuable resources. Fortunately, it is sometimes possible to […]

It’s Time to Automate Your Plasmid Purification

In the fifty years since the first reported transformation of recombinant plasmids into bacteria (1), plasmid cloning has become one of the pillars of synthetic biology research and manufacturing biopharmaceuticals. But purifying plasmids is no small feat. It can often take hours of hands-on time to go from culture to eluate with low-throughput and time-sensitive […]

Avoid the Cloning Blues This Season

I was blasting a holiday music playlist while driving recently, and Presley’s Blue Christmas played. I couldn’t get the phrase “Christmas Cloning Blues” out of my mind, and by the time I arrived at my destination, this happened: Cloning Blues Christmas (to the tune of Blue Christmas by Elvis Presley) I’ll have a blue Christmas […]

Our Top Three Most-Viewed Blog Posts of 2022

In 2022, our bloggers wrote on topics ranging from monkeypox outbreaks to cultured meat in biotech labs to preventing the next pandemic. Our top three most-viewed blog posts this year have the commonality of Promega products helping to advance important research in different fields and push science a step forward in the world. Take a […]

Growing Our Understanding of Rose Rosette Virus Through Reverse Genetics

Researchers at Texas A&M University are using a minireplicon, reverse genetics system to characterize the lethal Rose rosette emaravirus. Recently, they identified three changes to the reference genome sequence that negatively impacted viral replication.