Raising Frogs Takes a Village: Accelerating Amphibian Research at the Marine Biological Laboratory

Sally Seraphin’s life in the research lab started with rats and roseate terns. Chimpanzees and rhesus macaques came next, then humans (and a brief foray into voles). When she pivoted to red-eyed tree frogs, Sally once again had to learn all kinds of new techniques. Suddenly, in addition to new sample prep and analysis techniques, […]

For Frogs, Surviving the Heat Could Come Down to What Is in Their Gut

Amphibians are the most threatened vertebrate class worldwide. Because they lack the ability to regulate their own temperature and moisture levels, climate change is playing a significant role in this growing peril (1). Climate change impacts amphibian survival in several ways. In addition to habitat loss, growing drought conditions make maintaining body moisture levels challenging […]

The R&D Flex Team: A Unique Research Scientist Opportunity

Sarah Mahan embraces change. In fact, she doesn’t just embrace it, she seeks it out, running towards change with arms wide open.  “If I could do a different thing every week, I would. That’s what my job would be.” Sarah made her dream a reality when she began leading the Promega R&D Flex Team. This […]

Cancer Preventing Vaccines: Unleashing the Potential of Tumor Antigens

It has been more than 100 years since Dr. William B. Coley, known today as the “Father of Immunotherapy,” made the first recorded attempt to mobilize the immune system as a means of treating cancer (9). Decades later, the discovery of T cells and the vital role they play in the immune system set the […]

How Does Ozempic Work? The Mechanism of Action of Semaglutide and Other GLP-1 Receptor Agonists

In early 2023, a type 2 diabetes medication, semaglutide (brand names Ozempic, Rybelsus), drew huge amounts of attention on social media and in popular culture. The reason? People were getting off-label (that is, not for treating type 2 diabetes) prescriptions of Ozempic to take advantage of one of its common side effects—measurable weight loss. How […]

Exploring Instrumentation for Your Lab: Particle Movers vs. Liquid Handlers

Some laboratory processes are time-consuming and tedious. Automation highly manual processes such as nucleic acid extraction can increase your lab’s throughput and improve the overall consistency of your results. Unfortunately choosing and implementing one of these systems can seem overwhelming. As you begin to evaluate the automation needs of your lab, one of the first […]

No Horsin’ around with Halal Meat Authentication

Today’s blog is written by guest blogger, Sameer Moorji, Director, Applied Markets.   People’s diets are frequently influenced by a wide range of variables; with environment, socioeconomic status, religion, and culture being a few of the key influencers. The Muslim community serves as one illustration of how culture and religion can hold influence over people’s […]

Streamlining Disease Diagnostics to Protect Potato Crops

The mighty potato—the Midwest’s root vegetable of choice—is susceptible to a variety of diseases that, without proper safeguards, can spell doom for your favorite side dishes. Founded in 1913 and housed in the Department of Plant Pathology at the University of Wisconsin-Madison, the Wisconsin Seed Potato Certification Program (WSPCP) helps Wisconsin seed potato growers maintain […]

Supporting CAR-T Cell Therapy with STR Analysis

Engineered T-cell therapies, specifically CAR-T cell therapies, have emerged as a breakthrough treatment for certain types of blood cancers including lymphomas, some forms of leukemia, and most recently, multiple myeloma. CAR (chimeric antigen receptor) T-cell therapy involves collecting T cells from a patient and re-engineering them to detect and destroy cancer cells.

Have No Fear, qPCR Is Here: How qPCR can help identify food contamination

Foodborne disease affects almost 1 in 10 people around the world annually, and continuously presents a serious public health issue (9). More than 200 diseases have evolved from consuming food contaminated by bacteria, viruses, parasites, and chemical substances, resulting in extensive increases in global disease and mortality rates (9). With this, foodborne pathogens cause a […]