Studying the Genetic Basis of Type 2 Diabetes with An Automated Maxwell® Workflow

Over the past few decades, the prevalence of diabetes has been on the rise. According to the WHO, 422 million people worldwide have diabetes, causing an estimated 1.5 million deaths every year. Among those with diabetes, 95% have type 2 diabetes—which is caused by the body’s resistance to insulin. It is known that risk factors […]

Finding the Right Maxwell® RSC Kit for Your Nucleic Acid Extraction

This blog was written by guest writers Paraj Mandrekar (Technical Services Scientist 3) and Michelle Mandrekar, (Research Scientist 4). Here are some designer’s notes comparing the Maxwell® RSC Blood DNA and the Maxwell® RSC simplyRNA kit chemistries for nucleic acid extraction. The Maxwell RSC Blood DNA Kit and Maxwell RSC simplyRNA Blood Kit were both […]

Fighting Plant Pathogens Worldwide with the Maxwell® RSC PureFood GMO and Authentication Kit

Among the one trillion or so species that share space on our planet, complex relationships have emerged over time. Such relationships, in which two or more species closely interact, are collectively termed symbiosis. Although it’s commonly assumed that symbiotic relationships are mutually beneficial, this example constitutes only one type of symbiosis (known as mutualism). The […]

Ramping Up COVID-19 Testing with the Maxwell® HT Viral TNA Kit

John Longshore admits that he was not a big Promega customer before the COVID-19 pandemic. His team uses a wide variety of suppliers to assemble the types of testing protocols needed to serve over 50 hospitals. However, when he began to face supply chain disruptions in early 2020, he needed a supplier he could depend […]

Public-Private Initiative to Increase COVID-19 Testing Capacity by Using Promega Maxwell Instrument in India

This blog is written by guest blogger, Dr Rajnish Bharti, General Manager of Promega Biotech India Pvt Ltd. As COVID-19 cases accelerate, the country of India has decided to scale up testing capacity to 100,000 tests per day in the coming days. In a major step to counter the coronavirus crisis, Promega India is supporting […]

The Making of a Promega Product: Teamwork = Success for the Maxwell RSC® ccfDNA Plasma Kit

Ever think about the kinds of challenges R&D scientists run up against in the course of developing a new product? The development of the Maxwell® RSC ccfDNA (circulating cell-free DNA) Plasma Kit is a particularly interesting example. Its path to commercialization was characterized by a number of unexpected technical hurdles, yet each was overcome through […]

Freedom to Focus: Maxwell® Rapid Sample Concentrator

Back in the dark ages, when I was a graduate student, my idea of “automated” plasmid DNA extraction involved performing home-brew, “toothpick preps” in “strip tubes” or , if I was really feeling ambitious, a 96-well plate. I would get just enough DNA to check for the presence of an insert, but the quality of […]

A Virus Makes a Comeback: Emerging Poliovirus Transmission in the West

In 1921, at age 39, Franklin D. Roosevelt, the man who would later be elected the 32nd president of the United States, was diagnosed with polio (poliomyelitis). His symptoms included fever, gastrointestinal issues, numbness, and leg and facial paralysis. The disease left him paralyzed from the waist down, relying on a wheelchair and leg braces […]

Improved FFPE Tissue Sample Processing with High-Throughput Automated DNA Extraction

In oncology, tissue biopsies are commonly fixed in formalin and embedded in paraffin (FFPE). These FFPE samples can be used with immunohistochemical or molecular analysis for identifying biomarkers that guide the diagnosis and therapeutic management of patients. This fixation technique allows long-term storage of samples but impacts the integrity of nucleic acids. This makes extracting […]