Chuckle, It Is Friday

It is Friday. Maybe you have had a great week, a bad week, or maybe it was just average. No matter what kind of a week you have had, on Friday everyone should have something to chuckle about to end the week. Below are a few cartoons from our Cartoon Lab. I hope that you find one that tickles your funny bone.

Terminology is Important

Ed Himelblau: Giant Squid Axon

 Bigger is Not Always Better

Ed Himelblau: Macropipette

Timing Matters

Ed Himelblau: Mitosis Started

The Where, The Why and The How: A science writer and a graphic designer have a conversation

0the-where-the-why-and-the-how-75-artists-illustrate-wondrous-mysteries-of-scienceWhen I first learned that I had won a copy of The Where, The Why and The How in the book lottery at ScienceOnline 2013, I couldn’t believe my luck. I never win anything, at least not anything that I actually want. And I wanted a copy of this book.

The book is beautiful to hold. The linen binding is beautiful, reminiscent of bygone days when book binding was a practiced art. The paper is thick and smooth, a tactile pleasure as you turn each page; the pages themselves sound substantial as you flip through the book. Even the smell of the book is delightfulโ€”bringing to mind the stacks of old books filling a great library, even though what you hold in your hand is a new work. The science paisley inside covers of the book are a delight to look at, comprising various science icons intricately woven into an astounding tapestry.

I was expectant when I opened the book for the first chance for a serious read. Continue reading “The Where, The Why and The How: A science writer and a graphic designer have a conversation”

Copper Containing Surfaces and Their Potential for Reducing the Spread of Infection and Antibiotic Resistant Gene Transfer

As a scientist and a jewelry artist, there are not that many occasions when my two passions overlap. As a geneticist, I find the evolution and spread of antibiotic resistant microbes to be fascinating in a โ€œthis is really cool and utterly terrifyingโ€ sort of way. As a jewelry artist, I love experimenting with new and different metals. Some of my current favorites are stainless steel, copper and bronze, which is an alloy of copper and tin. So you might be able to imagine my excitement when I came across an article in mBio discussing the public health implications of horizontal gene transfer (HGT) of antibiotic resistance genes on clinical and public touch surfaces made from copper alloys compared to those made of stainless steel (1).

Stainless steel: The unexpected, gene-transferring truth

Polishing stainless steelStainless steel is often used in clinical and public settings as work surfaces as well as other surfaces that are touched and cleaned often. Stainless steel is used in these applications for many of the same reasons I like it for jewelry: it is strong, resilient, relatively inexpensive, stain- and corrosion-resistant and will weather regular cleaning/exposure to moisture well. There is something about a gleaming stainless steel work surface that looks, well, sterile. But is it? Continue reading “Copper Containing Surfaces and Their Potential for Reducing the Spread of Infection and Antibiotic Resistant Gene Transfer”

Uniquely Buried in a Wisconsin

WinterIt is winter in Wisconsin, and it has arrived with a blizzardyย vengeance. My family and I are snowed in for the second day, and as I write this I am trying not to think of the twelve plus inches of snow that covers my driveway. I am afraid to measure the height of the drifts.

The world outside my window is beautiful. Tree limbs and fence posts are frosted in white. There is a LOT of snow out there, and that made me stop and think, there is an awful lot of uniqueness out there. IF every snowflake is unique. And according to a local Wisconsin snowflake expert,ย Universityย of Wisconsin, Madison, meteorology professorย Pao Wang, they aren’t. Continue reading “Uniquely Buried in a Wisconsin”

Rats Avatars: A New Twist On Virtual Reality

Imagine playing a simple game in a virtual-reality setting. You move an avatar around a room trying to entice your opponentโ€™s avatar to move closer to you when you are in certain spot. Meanwhile, 12 km away, cameras track your opponentโ€™s movements around an arena that also contains a robotic representation of you. The cameras are telling your opponentโ€™s avatar where to move in your virtual reality setting based on where they move in their actual setting.

Your goal is to score the most points by moving the virtual you into proximity with your opponentโ€™s avatar while you are both at a certain location within the virtual room. If you succeed, you score a point. If you and your opponent get too close anywhere else in the room, your opponent scores a point. Your opponent, however, is not terribly interested in points; your opponent wants to get close to the robotic you because it has snacks. Your opponent is a rat, Continue reading “Rats Avatars: A New Twist On Virtual Reality”

Having Fun at Work

Last week we had a celebration honoring employees who have reached milestone 5, 10, 15, 20, 25, and even 30 years here at Promega. As part of the festivities we made a fun “Lip Dub” video that involved many of our coworkers based here in Madison and around the world. We’d like to share the video here. Enjoy!

[youtube http://www.youtube.com/watch?v=j7dgsThYVyU&w=560&h=315]

How to Make Plastic Out of Milk

As the daughter of a (former) dairy farmer, I love milk and all its derived dairy products (e.g., cheese and butter). However, it wasn’t until my colleague Michele highlighted a kid science app that I realized milk is a great science medium as well. In fact, I recently discovered mixing vinegar with milk will create moldable plastic. Not only is this milk-derived product fun for kids and adults, but it also offers a history lesson: the resulting substance was used before petroleum-based plastic was available. Watch the video to learn about a fun kitchen experiment and potential handmade gift opportunity all in one package.

[youtube=http://www.youtube.com/watch?v=VFvik_THcNQ]

It’s the crunchy bits I like the best

I was supremely lucky this past fall to get six delicious fresh figs. It’s a rare treat for me since figs have such a short season and an even shorter shelf life. This year, I nearly had to leg wrestle my way to the bin at the store to score some of these fresh beauties.ย I had commented to another patron at the store that I couldn’t wait to get these little fellas home, stuff them with some goat cheese, wrap them in a bit of bacon, give them a quick balsamic and honey glaze, and pop them into the oven. Now, tender, sweet figs stuffed with rich, herbed goat cheese and wrapped with what is, quite possibly, the world’s most perfect meat makes me weak in the knees. The bacon, of course, is sublime, but the sweetness of the figs with the delicate crunch of those seeds really sells it.

My fellow shopper replied with “Well, good for you. I couldn’t possibly eat any of that. I’m vegan.” ย Fair enough. In a past life, I worked as a personal chef and did a tremendous amount of work with vegetarians and vegans alike.ย Although I may never personally understand a life without cheese, I can respect it and I can certainly cook in that fashion.

One portion of that exchange, however, didn’t quite seem right. I actually followed Mr. Vegan (I didn’t ask his name) into the next aisle and asked for some clarification.ย “I’m sorry,” I continued, “but what did you mean by you couldn’t eat any of it? Cheese and bacon are out, but who could ever turn down a looker like this?” I asked, tapping my fresh figs ever so gently.

He just smiled and told me to look it up. Harrumph. Continue reading “It’s the crunchy bits I like the best”

For the Love of Squash

The weather is getting colder, and the leaves are changing color; fall is upon us. Itโ€™s time to pull out your sweaters and scarves and cozy up under a blanket. Itโ€™s time to pick apples, carve pumpkins and eat one of my favorite comfort foodsโ€”winter squash.

Here at Promega our culinary team tends a garden onsite, filling our menus and plates with amazingly fresh and local produce. Our constantly changing breakfast and lunch menus are just as good of an indicator of the season as the calendar. This time of year dishes with tomatoes, beans and eggplant are disappearing and are being replaced winter squash, potatoes and root veggie dishes. Winter Squash Soup is starting to show up on the menu and Nate Herndon, our head chef, has been kind enough to share one of his favorite recipes with us. Continue reading “For the Love of Squash”

Happy Birthday to You: Are Your Hands Clean?

My daughter has been actively planning her birthday for about three weeks now (and she still has almost two months to wait). At the top of her wish list this year? Hand sanitizer. As my kids headed back to school this week, I noticed that one of the most popular pieces of backpack โ€œblingโ€ among her little friends was little bottles of: you guessed it, hand sanitizer. In bright colored silicone covers, with yummy sounding scents, little bottles of hand sanitizer bounced along on the backpacks of a lot of the youngsters walking into the school.

The first thought that might come into your head is โ€œWow. Those kids are going to be so healthy. All those nasty germs might as well look elsewhere for victims.โ€ And you would be at least partially right. Proper hand hygiene can decrease the transmission of cold viruses as well as other germs, and hand sanitizer can play a part in good hand hygiene when it is used properly and in the right quantity.

What hand sanitizer can not do is take the place of washing hands. It does not, for instance, remove dirt or other contaminants. (Although it can help smear the dirt around so that it forms a more evenly dispersed layer, prompting your child to claim their hands have been cleaned). Hand sanitizers also will not effectively eliminate nonenveloped viruses such as the norovirus. These are the nasty little things that are responsible for the majority of acute gastrointestinal illnesses. (1,2,3). In fact, using hand sanitizers may actually increase the spread of these viruses if it results in a decrease of hand washing with soap and water.

Hand sanitizers that are most effective contain ethyl alcohol (62% to 95% concentration), benzalkonium chloride, salicylic acid, pyroglutamic acid, and triclosan. These ingredients, while making the sanitizers effective against some germs, also dry out the skin and destroy some to the naturally existing fauna on the skin, which gives other germs a chance to take hold. An example is Clostridium difficile. This gram-positive, spore-forming bacteria can cause severe intestinal upset and diarrhea when competing bacteria in the digestive track have been wiped out by antibiotics. A 2010 study found that some people who were over reliant on sanitizers had C. difficile spores colonizing on their hands (4).

C. difficile infections are probably not a big risk for the average school-age child, but the example highlights the fact that hand sanitizers are not the silver bullet of hand hygiene that they are sometimes portrayed to be. The center for Disease Control and Prevention (CDC) in the U.S. lists the following guidelines for hand washing:

  • Wet your hands with clean running water (warm or cold) and apply soap.
  • Rub your hands together to make a lather and scrub them well; be sure to scrub the backs of your hands, between your fingers, and under your nails.
  • Continue rubbing your hands for at least 20 seconds. Need a timer? Hum the “Happy Birthday” song from beginning to end twice.
  • Rinse your hands well under running water.
  • Dry your hands using a clean towel or air dry.

Washing hands with soap and water is the best way to reduce the number of germs on them. If soap and water are not available, use an alcohol-based hand sanitizer that contains at least 60% alcohol. Alcohol-based hand sanitizers can quickly reduce the number of germs on hands in some situations, but sanitizers do not eliminate all types of germs. (5).

My daughterโ€™s birthday is still two months away, but I am going to suggest to her that she start practicing for it now. I am going to suggest she sing โ€œHappy Birthdayโ€ to herself twice while washing her hands, and leave the hand sanitizer on her backpack for those times when soap and water are not available.

References

  1. Liu P, Yuen Y, Hsiao HM, Jaykus LA, Moe C. (2010) Appl Environ Microbiol.ย 76, :394โ€“9.
  2. Hand sanitizers may actually cause outbreaks of norovirus. Medical New Today website. ww.medicalnewstoday.com/articles/232708.php. Accessed August 29, 2012.
  3. Hall AJ, Vinjรฉ J, Lopman B, et al. Updated norovirus outbreak management and disease prevention guidelines. Centers for Disease Control and Prevention website. www.cdc.gov/mmwr/preview/mmwrhtml/rr6003a1.htm. Accessed August 29, 2012.
  4. Jabbar, U., Leischner, J., Kasper, D., et al. (2010) Infect Control Hosp Epidemiol. 31, 56โ€“70.
  5. CDC website http://www.cdc.gov/features/handwashing/ Accessed August 29, 2012.