Last summer, we announced our most ambitious sustainability goals ever. This year, as part of our annual reporting, we are proud to share that over 20% of our global electricity is supplied by renewable sources. This represents a ten-fold increase in our renewable energy usage over the past three years.
Continue reading “Promega Sourcing Over 20% of Global Electricity from Renewable Sources”After a long hiatus sparked by the COVID-19 pandemic, the Promega Art Showcase will return next week with a new exhibition titled “A Vibrant Welcome Back!”
Why is a biotechnology company hosting an art show?
At its core, science is rooted in creativity. Scientists investigate the unknown and search for novel solutions that can improve our quality of life. We believe that observing and creating art reenergizes the imagination, inspiring scientists to look from new perspectives and step outside of the norms.
Promega has hosted quarterly art showcases in the BioPharmaceutical Technology Center since 1996. These showcases are open to the public and have featured the work of local, national and international artists. Past shows have included sculptors, folk artists, photographers, and painters. The December-March show each year features artwork by Promega employees and their family members.
The 2022 Summer Art Showcase features the work of Derrick Buisch, a painter and professor at the University of Wisconsin-Madison, alongside Bettina Madini, a European contemporary artist and fashion designer.
Continue reading “A Vibrant Welcome Back to the Promega Art Showcase”
“Are you going to the talk?”
The refrain regularly echoes through the halls of every academic lab building. During our education, we’re treated to a non-stop supply of speakers on every subject we can imagine. Prestigious speaker series gave us chances to hear from some of the world’s most prominent experts on subjects that would shape scientific pursuits for the next decade and beyond. When we leave academia, however, it can be difficult to find those same opportunities to learn. Sure, there are lab meetings and conferences, but when can you be treated to a renowned expert giving a talk just down the hall?
Promega Head of Biology Frank Fan aimed to address that problem when he developed a plan for the Kornberg Innovation Seminars (KIS), a recurring speaker series to be held in the new home for Promega R&D. Kornberg Center is an environment where Promega scientists are challenged to think outside-the-box and anticipate the challenges life science researchers will be facing tomorrow. Frank believed that opportunities to learn from a wide variety of guest experts would be critical for inspiring that type of thinking.
“Promega R&D focuses on understanding scientists’ needs and providing novel solutions,” Frank says. “The KIS program is about helping us achieve that vision.”
Continue reading “Kornberg Innovation Seminars: Inspiring Creativity in Promega R&D”
A new study published in Nature Chemical Biology shows that the most commonly mutated protein in cancer might not be as “undruggable” as previously believed. Promega R&D scientists collaborated with the research group led by Kevan Shokat at the University of California – San Francisco to develop strategies for targeting mutants of KRAS that have evaded previous drug discovery efforts. Their paper opens new possibilities for developing small molecule inhibitors against KRAS(G12D) and other clinically significant mutants.
Continue reading “Study Reveals New Strategies for Targeting “Undruggable” KRAS Mutants”
During the summer after my junior year of undergrad, I worked as a marketing intern for a health education nonprofit. I was a biology major, but by this time I knew I wanted to pursue a career in science writing, and this internship was my first real-world experience. It was an amazing summer, and by the time I walked into my exit interview, I was confident that my supervisor was pleased with my performance. However, she shared a piece of feedback that caught me off guard.
Continue reading “Transforming Your Fear In Meetings”Before the respiratory virus SARS-CoV-2 ever emerged, Tom Friedrich was already studying how viruses evolve to cause pandemics. His PhD training focused on how HIV adapts to escape detection by the immune system. Since opening his lab at the University of Wisconsin—Madison in 2008, he’s studied how viruses like influenza and Zika overcome evolutionary barriers to spread and cause disease. For nearly two years, he’s been analyzing viral sequencing data generated from positive COVID-19 test samples around the state of Wisconsin.
As the COVID-19 pandemic persists, Tom continues to make important contributions to both SARS-CoV-2 research and the relevant public health response. However, his experiences have led him to ask an even bigger question: How can we prepare for the next pandemic while still battling the current one?
“What has characterized our responses to these types of disease outbreaks in the past is sort of a boom and bust cycle,” Tom says. “We spin up a massive response that often tends to get going just as the thing itself is petering out. Then interest and funding wane so that we’re not really left with any sustainable infrastructure. But with Ebola, Zika and now COVID-19 in a pretty rapid cadence, I think people are finally getting the idea that we need to have a more sustainable infrastructure that is not totally specific to the particular disease that’s causing this outbreak today.”
Continue reading “Can We Prevent the Next Pandemic?”
The BioPhamaceutical Technology Center Institute (BTC Institute) is a non-profit organization that provides opportunities for people of all ages to learn about life science and biotechnology. This summer, BTC Institute hosted a variety of programs supporting teachers, potential first-generation college students, and many other groups. Each program supports an overall goal to support scientific understanding in our community.
BTC Institute has collaborated with the African American Ethnic Academy in Madison, WI for over 25 years to offer a summer science program for upper elementary and middle school students. This year, A Celebration Of Life XXVI welcomed 13 students from grades 4-8 every morning for two weeks. Students made ice cream, engineered water filtration devices, and used bioluminescence to learn about preventing the spread of germs. Outside the lab, the students learned tai chi from a Promega employee and toured the Promega culinary garden. Along the way, students learned about historic and contemporary STEM professionals of color associated with each focus area, including astronaut Victor J. Glover and teen entrepreneur Nabil Hamdan.
Continue reading “BTCI Summer Programs Provide Learning Opportunities to All Ages”
In the summer of 2000, Promega research scientist Allan Tereba was asked to develop an automated protocol for purifying DNA for forensics. His team had recently launched DNA IQ, the first Promega kit for purifying forensic DNA using magnetic beads. This was before the Maxwell® instruments, and before Promega purification chemistries were widely adaptable to high-throughput automation.
“I had my doubts about being able to do that,” Allan says. “When you’re working with STRs, small amounts of contaminant DNA are going to mess up your results. But I went ahead and tried it, and it was a challenge.”
A little over a year later, Allan was in his office when he heard on the radio that a plane had struck the North tower of the World Trade Center in New York City. Shortly after, he heard the announcement that a second plane had hit the South tower.
By that point, Allan and his colleagues had successfully adapted DNA IQ to be used on the deck of a robot. Within days of the attacks, Promega scientists were supporting the New York City Office of Chief Medical Examiner (OCME) and New York State Police in their work to identify human remains that were recovered from Ground Zero.
Thanks to the work of Allan and many other Promega scientists, Promega was prepared to offer unique solutions to urgent needs. In their own words, here are some of those scientists’ reflections.
Continue reading “Automating Forensic DNA Purification to Meet Urgent Needs: Reflections on September 11, 2001”The Delta Variant poses a unique challenge to global health. We’ve compiled answers to some of the most common questions about Delta and other SARS-CoV-2 variants.
A variant is a form of a virus that is genetically distinct from the original form.
“All organisms have mutation rates,” says Luis A Haddock, a graduate student at University of Wisconsin – Madison. “Unfortunately for us, viruses have one of the highest mutation rates of everything that currently exists. And even more unfortunately, RNA viruses have the highest mutation rates even among viruses.”
Luis works in the Friedrich Lab at UW-Madison, which has been sequencing SARS-CoV-2 genomes from positive test samples since the beginning of the pandemic. SARS-CoV-2 is constantly evolving, and sequencing can help us follow it through time and space. Most of the variants don’t behave any differently. A single nucleotide substitution might not even change the amino acid sequence of an encoded protein. However, occasionally a mutation will alter the structure or function of a protein.
Learn more about SARS-CoV-2 sequencing in the article “From Primate Models to SARS-CoV-2 Sequencing and Testing,” featuring David and Shelby O’Connor, two collaborators of the Friedrich Lab.
The Promega Corporate Responsibility Report captures a variety of stories of how we’ve supported our employees, customers and communities over the past year. For example, in 2020, 735 million samples were tested for SARS-CoV-2 using Promega reagents. We launched a new scholarship to support students from underserved backgrounds, and we completed our three largest solar arrays on our Madison, WI campus. As we look to the future, we recognize that there are always more opportunities to reduce our environmental impact. That’s why we’re setting our most ambitious sustainability goals ever.
Continue reading “2030 Sustainability Goals: Our Most Ambitious Ever”