Supporting CAR-T Cell Therapy with STR Analysis

Engineered T-cell therapies, specifically CAR-T cell therapies, have emerged as a breakthrough treatment for certain types of blood cancers including lymphomas, some forms of leukemia, and most recently, multiple myeloma. CAR (chimeric antigen receptor) T-cell therapy involves collecting T cells from a patient and re-engineering them to detect and destroy cancer cells.

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The Power of Pet Ownership

International Pet Day, observed each year on April 11th, provides the purrfect opportunity to reciprocate all the labored love and affection our pets so freely give us. There’s no doubt that our furry, feathered, and scaley friends greatly improve our quality of life. But did you know there are benefits to this human-animal bond beyond their incredible cuteness? Read about some of the paw-some science-approved benefits that can come with pet ownership.

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3.14 Ways to Make Pi Day a Piece of Cake!

Celebrated each year on March 14th (3.14), Pi Day commemorates the irrational, transcendent, and never-ending ratio that’s used to represent a mathematical constant. This infinite number is crucial when describing circles because no matter how big or small, the ratio of a circle’s circumference to its diameter will always equal to pi.

In 2009, pi day, also written π or 3.14, was declared an official national holiday–one that’s worth celebrating! We’ll help you kick things off with 3 fun facts, 1 joke, and 4 activities that are certain to get you in the Pi Day spirit.

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suPAR: A New Approach to Treating Cardiovascular Disease

Cardiovascular disease (CVD), continues to be the leading cause of death in the United States and worldwide. Many patients with CVD have signs of chronic kidney disease (CKD), and those with CKD are often times disproportionately affected by CVD.

This interconnectedness was further explored in a recent study published in the Journal of Clinical Investigation that identified a new immune target, suPAR, as a protein that causes kidney disease and atherosclerosis, the most common form of CVD. Unlike traditional approaches to treating CVD such as controlling blood pressure and lowering cholesterol, this breakthrough research offers a new approach to treatment from an entirely different perspective.

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Exploring Investigative Genetic Genealogy 

In the past few years, and as seen as a popular topic at ISHI 33, investigative genetic genealogy (IGG) has rapidly grown and emerged as a new field of science to identify human remains or cold case crime scene samples. The technique traces potential genetic familial relationships through DNA databases. Although genetic genealogy and public DNA databases have been around for quite some time, what’s new is their use by law enforcement.

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Our Top Three Most-Viewed Blog Posts of 2022

In 2022, our bloggers wrote on topics ranging from monkeypox outbreaks to cultured meat in biotech labs to preventing the next pandemic. Our top three most-viewed blog posts this year have the commonality of Promega products helping to advance important research in different fields and push science a step forward in the world. Take a look at Promega’s top three most-viewed blog posts of 2022.

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What’s New with Promega Resources?

Whether you’re looking to learn about nucleic acid analysis, wondering how to do an ELISA assay, or simply have ten minutes to kill in your day, Promega resources have you covered! We’ve revamped and upgraded our hub of self-service resources so we can provide the most up-to-date scientific support. Here are some highlights of what’s new:

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What Have You Done for Your Emotional Wellness, This Month? 

Most of us are familiar with the term wellness. We associate wellness with lifestyle practices such as exercising, having a balanced diet, and taking care of our bodies. As significant as these practices are to live long, healthy lives, there’s a critical component of wellness that is often overlooked, emotional wellness. 

The National Center for Emotional Wellness defines emotional wellness as, “An awareness, understanding and acceptance of our feelings, and our ability to effectively manage through challenges and change.” Maintaining a healthy emotional balance helps us form better relationships with peers, make healthier lifestyle choices, and empower people through life’s unexpected changes. October, Emotional Wellness Month, is the perfect reminder to take time out for your brain and make steps towards effectively managing your emotions.

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Onward with Online Learning!

National Online Learning Day is celebrated annually on September 15, and although it was only created in 2016, it’s a growing “day”. This day highlights students of all ages who have the ability to learn anywhere, anytime, and thrive wherever their technology and imagination take them.

Technology in the past decade has completely transformed and built bridges in education. Even before the pandemic, online learning was growing and being adopted. As we entered the COVID-19 pandemic, educational institutions were forced to think digitally, and our viewpoint of online education shifted from “option” to “necessity”.

Whether you’re enrolled in a virtual course, working from home, or sitting in on a virtual conference, nearly all of us, at some compacity, take part in online learning—and it’s here to stay! The ability to learn online will continue to provide people with new resources and support for many years to come. Let’s dive into some advantages of online learning and discover helpful resources to thrive online.

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How Fire Coral has an Edge Over Other Species in the Caribbean Reef

Coral reefs are the most productive marine ecosystem known, providing essential habitats and shelters for fish and other organisms. Additionally, they help protect coastlines, support economies, provide important food sources for local fisheries, and so much more. Coral reefs are ecologically essential—but are continuing to vanish. Fire coral (Millepora) brings new hope to this marine crisis due to their unusual ability to grow in two forms and survive under various habitat stresses.

Bladed fire coral (Millepora complanata) undersea, Caribbean Sea, Cuba, Playa Cueva de los peces
Bladed fire coral (Millepora complanata) undersea, Caribbean Sea, Cuba

What Is Fire Coral?

Fire coral has been around for millions of years and is most commonly found in sunny, shallow reefs. They tend to grow in tropical and subtropical waters with many thriving in different areas of the Caribbean Sea, one of the planet’s most biologically diverse ecosystems. Fire coral resembles typical stony corals but has a wicked sting that can cause burning skin reactions, reflecting their relationship as a close relative to jellyfish.

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