This year, our bloggers wrote about a range of topics, including semaglutide, a 20,000-year-old pendant, and type 1 diabetes. Each topic is unique and has proven its popularity by our Promega Connections readers! Take a look at our top three most-viewed blog posts of 2023.
1. How Does Ozempic Work? The Mechanism of Action of Semaglutide and Other GLP-1 Receptor Agonists
Earlier this year, semaglutide (brand names Ozempic, Rybelsus) gained widespread attention for its common side effect, measurable weight loss, leading to people seeking off-label prescriptions—not for treating type 2 diabetes.
In this blog post, read how semaglutide and other GLP-1 receptor agonists help manage type 2 diabetes on a molecular level. Learn how they contribute to weight loss effects, as well as future directions for additional therapies and treatments.
2. DNA from a ~20,000-Year-Old Pendant Offers Genetic Picture of Its Owner
Artifacts play a pivotal role in helping us understand the migration, behavior, and cultures of ancient peoples, as well as history. However, there are limitations to this information, such as providing insight into biological sex, genetic ancestry, and characterizing societal roles and behaviors. That is, until the discovery of one tiny pendant!
In this blog post, read about recent advances in DNA techniques and technologies and how one tiny pendant provides genetic knowledge of its ancient handler.
3. Monoclonal Antibody (mAb) Therapy to Delay the Onset of Type 1 Diabetes
The US Food and Drug Administration (FDA) recently approved the first drug to delay the onset of stage 3 type 1 diabetes (T1D). Teplizumab, the monoclonal antibody (mAb) drug, was approved in adults and pediatric patients 8 years and older.
In this blog post, learn how teplizumab works and how it affects people with type 1 diabetes.
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Riley Bell
