Immune checkpoint pathways such as PD-1/PD-L1 and CTLA-4 are promising new immunotherapy targets for the treatment of cancer and autoimmunity. Immune checkpoint reporter-based bioassays provide a simple, consistent, and reliable cell-based assay to measure Ab function throughout the drug development pipeline.
The brief chalk talk below describes the assay principals of the reporter-based bioassay that monitors the functional blockade of PD-1/PD-L1 interactions.
The following two tabs change content below.
Kelly Grooms
Scientific Communications Specialist at Promega Corporation
Kelly earned her B.S. in Genetics from Iowa State University in Ames, IA. Prior to coming to Promega, she worked for biotech companies in San Diego and Madison. Kelly lives just outside Madison with her husband, son and daughter. Kelly collects hobbies including jewelry artistry, reading, writing, photography and knitting. She would like to be an avid runner, as evidenced by her growing collection of running gear and her single half-marathon finishers t-shirt.
Latest posts by Kelly Grooms (see all)
- Fished to the Edge: How DNA Identification Can Help Fight the Illegal Trade of Threatened Shark Species - August 17, 2018
- Beneath the Writing: Non-Invasive DNA Sampling from Modern and Historic Writing Surfaces - July 17, 2018
- From Dating Apps to In Vitro Fertilization, the Challenges to Saving the Endangered Northern White Rhino - May 18, 2018