In February of 2011, tragedy struck when Dave Duerson, a former Chicago Bears football player, committed suicide by shooting himself (1). However, Dave was not alone; his suicide joined the suicides and other violent endings to former and current football players such as Andre Waters (Philadelphia Eagles, Arizona Cardinals), Owen Thomas (U. Pennsylvania), and Kenny McKinley (Pittsburgh Steelers).
One could shrug off the deaths of these players are simple coincidence, if not for an elusive, yet chilling, central theme found in the depths of their brains: small, yet insidious, neurofibrillary tangles containing the microtubule-associated protein tau. Such tau-containing tangles are the molecular hallmarks of frontotemporal dementia (FTD) or Alzheimer’s Disease-riddled brains. The brains of people who are not diagnosed with FTD or Alzheimer’s Disease do not contain these tau tangles.
If that is the case, why in the world were Dave Dueson, Andre Waters, Owen Thomas and Kenny McKinley found to have these tau tangles? Continue reading “What Does Tau Protein Have to Do with Football, Dementia, and Suicide?”