A Potential Single-Tube Multiplex Assay for Detecting Dengue Virus in the Field

Countries affected by dengue. By Percherie (Distribution de la dengue sur Commons) [GFDL (http://www.gnu.org/copyleft/fdl.html), CC-BY-SA-3.0 (http://creativecommons.org/licenses/by-sa/3.0/) or CC BY-SA 2.5-2.0-1.0 (http://creativecommons.org/licenses/by-sa/2.5-2.0-1.0)], via Wikimedia Commons
In areas of the world where the electricity is intermittent, resources are limited and transporting bulky equipment and reagents that are sensitive to temperature fluctuations is difficult, diagnosis of viruses like dengue can be challenging. If you could reduce or eliminate the need for electricity dependent equipment for diagnostic assays without sacrificing sensitivity or specificity, it would be a boon to field workers. An article published in PLOS ONE describes how researchers developed a multiplex isothermal amplification method that could assess a potential dengue infection with a visual real-time or endpoint detection in a single tube. Continue reading “A Potential Single-Tube Multiplex Assay for Detecting Dengue Virus in the Field”

Breast Cancer(s) Heterogeneity and Personalized Treatments

Image used with permission of Dr. Hongdi Liu.
Image used with permission of Dr. Hongdi Liu.
Recently Promega hosted a special guest from Duke University—Dr. Neil. L. Spector, one of leading scientists in the field of breast cancer research. In a simple way  Dr. Spector presented advances in this field of cancer research and informed us of new treatments that have the potential to improve patient lives. Continue reading “Breast Cancer(s) Heterogeneity and Personalized Treatments”