Why Hasn’t the “Alternative” Become Mainstream?

Pearl Jam, a popular alternative rock band in the 1990s (and still pretty awesome!). Photo credit: Rolling Stone Magazine.

This post could easily start out as an ode to ’90s alternative music (of which I’m a huge fan). That new and totally different sound (a la Pearl Jam, Smashing Pumpkins, Soundgarden, Nirvana, etc.) in the 1990s eventually made its way into the mainstream as it gained popularity. (I have to say that I got a shock when I recently heard some Pearl Jam on “classic rock” radio stations. But I digress…)

Why isn’t the same true for science career paths? Science careers outside of academia are still referred to as “alternative.” In a previous post, I highlighted statistics from a 2012 NIH report that found that only 20% of recent life sciences Ph.D.’s go on to become faculty members1. That means that 80% of recent life sciences Ph.D.’s took the “alternative” path. It seems like the academic path could now be viewed as the alternative to the mainstream, but somehow there’s an underlying stigma associated with straying from a path which few can travel down successfully.

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Celebrating Women in Science

By US Environmental Protection Agency [Public domain], via Wikimedia Commons

February 11 is the International Day of Women and Girls in Science, a reminder that there is still a gender gap in science. Despite the obstacles that women need to overcome, their contributions to field of science have benefited not only their fellow researchers but also their fellow humans. From treatments for diseases to new discoveries that opened up entire fields, women have advanced knowledge across the spectrum of science. Below is a sampling of the achievements of just a few women in science. What other living female scientist or inventor might you add?

Hate malaria? You can thank Tu Youyou for discovering artemisinin and dihydroartemisinin, compounds that are used to treat the tropical disease and save numerous lives. Her discovery was so significant, she received the 2015 Nobel Prize in Physiology or Medicine.

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Encouraging, Supporting, and Advocating for Diversity in Science

On December 27, 2017, the life sciences community lost a pioneer in neurobiology and an advocate for equality in science. Dr. Ben A. Barres passed away at the age of 63. His work focused on the critical role of glia (non-neuronal cells) in the brain and how they interface with neurons to maintain cognitive function.

Equally remarkable was the more personal side of his life. In 1997, Dr. Barbara Barres transitioned from female to male and lived the remainder of his life as Ben Barres. I read a number of the articles that Dr. Barres wrote and came across one that particularly caught my attention. In 2006 in response to several statements blaming gender imbalance in STEM fields on women’s innate in-aptitude, Ben wrote a Commentary in Nature that touched on his experience as a female scientist versus how he was treated as a male scientist. (Dr. Barres makes many very interesting points in the article, so I would encourage anyone to read it.) Prior to transitioning, he was often dismissed or interrupted but had a completely different experience as a male scientist. Dr. Barres even recounted that he overheard a colleague praising a seminar he gave, and adding that his work was “much better than his sister’s”1. The colleague was unaware that the research was the same and that he was talking about the same person. What a unique perspective to have been the one in the position of discrimination and then to be removed from it.

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Cholesterol Management and the Importance of Diversity in Clinical Trials

Source: National Heart, Lung and Blood Institute
Source: National Heart, Lung and Blood Institute

According to the National Heart, Lung and Blood Institute (1), 50% of women in the US have high or border line cholesterol levels and cholesterol level tends to increase as we age. Most of you are probably aware that cholesterol levels are important for health. Cholesterol is a waxy, sticky molecule that is a very important part of your cellular make up, so cholesterol is essential for life. However, if we have too much cholesterol circulating in our blood, it can build up along artery walls and create blockages (plaques) leading to heart attacks or strokes.

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