Author: Teresa Simon

Invisible Leishmaniasis: How a One Health Approach Changed Everything in Honduras

Posted on by Teresa Simon

Imagine a parasite circulating actively in a community, infecting dogs, spreading through insect vectors, moving between multiple species—and no one notices. Not because people aren’t looking, but because traditional disease surveillance only watches clinical cases in humans, missing the invisible circulation happening all around them. Research on emerging zoonotic diseases confirms this dynamic is not unique to Honduras, it reflects a global risk intensified by urbanization and climate change. Read more about this in our Promega Connections blog (2).

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CRISPR/Cas9 Endogenous Tagging in Drug Discovery

Posted on by Teresa Simon

Limitations of Traditional Protein Study Methods 

Studying proteins in their native biological context has long been a major challenge in molecular biology. Traditional methods, although widely used, often distort the actual cellular environment and limit functional interpretation. Techniques like antibody-based detection or plasmid-driven overexpression can introduce artifacts and do not allow real-time analysis in living cells. 

In this context, the need for tools that enable the observation of proteins as they naturally occur, under physiological conditions, and within live cells is becoming increasingly evident in molecular biology. 

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