Bioluminescence and Biotechnology: Shining Nature’s Cool Light on Biology

Imagine you’re taking a refreshing night swim in the warm blue waters of Vieques in Puerto Rico. You splash into the surf and head out to some of the deeper waters of the bay, when what to your wondering eyes should appear, but blue streaks of light in water that once was clear. Do you need to get your eyes checked? Are you hallucinating? No! You’ve just happened upon a cluster of dinoflagellates, harmless bioluminescent microorganisms called plankton, that emit their glow when disturbed by movement. These dinoflagellates are known to inhabit waters throughout the world but are generally not present in large enough numbers to be noticed. There are only five ecosystems in the world where these special bioluminescent bays can be seen, and three of them are in Puerto Rico. 

Bioluminescent plankton exhibit a blue glow when disturbed.
Bioluminescent plankton in the ocean

But you don’t have to travel to Puerto Rico or swim with plankton to see bioluminescence. There are bioluminescent organisms all over the world in many unexpected places. There are bioluminescent mushrooms, bioluminescent sea creatures—both large and small (squid, jellyfish, and shrimp, in addition to the dinoflagellates)—and bioluminescent insects, to name a few. Bioluminescence is simply the ability of living things to produce light.

Continue reading “Bioluminescence and Biotechnology: Shining Nature’s Cool Light on Biology”

Meeting the Needs of Scientists at All Levels

One of the best things about the BTC Institute is that we have programs for all levels of learners. It is as rewarding to introduce the concept of how bioluminescence is used by different organisms in the natural world to middle-school students as it is to have top-level scientists use reporter genes to track their knock-in genome edits.

We spend a lot of time working over our curricula to determine whether the content meets the learner where they are to allow our students to achieve their goals. We develop activities that let students who comes to us —via field trips, high school courses, non-scientist sessions and graduate level programs—to test ideas and evaluate strategies for problem solving as they learn techniques and concepts central to biotechnology. Continue reading “Meeting the Needs of Scientists at All Levels”

Introduction to the Laboratory: A New Workshop in Partnership with the UW-Madison Center for Educational Opportunity

During the week of March 26, 2018, while many students were having fun and relaxing during Spring Break, others were busy doing extra lab work at the BTC Institute. This four-day workshop was designed to provide an introduction to the molecular biology laboratory for students affiliated with the Center for Educational Opportunity (CeO) on the UW-Madison campus.  As noted on its website: “CeO promotes access to resources, academic achievement and personal growth for students whose parents have not received a four-year degree, students who meet specific federal family income guidelines, and students with documented disabilities.”

It is well known that first-generation college students, women and students of color persist in STEM fields at lower rates than the general population. This interferes with the creation of a diverse STEM talent pool, in turn needed to ensure diverse problem-solving perspectives.

Further, STEM fields are often seen as being stressful, given their competitive learning environments.  This may be especially discouraging for students from racial/ethnic minorities who may not have as many mentors and role models to turn to.

Group photo of attendees
Introduction to the Laboratory attendees

This workshop aimed to give students an experience that would strengthen their skills and confidence as they continue to pursue scientific paths. In addition to laboratory work, students discussed the importance of clear communication in written and oral presentations, were required to work as partners to experience teamwork, and were encouraged to use reflection and lab reporting as ways to internalize what they learned throughout the week. Continue reading “Introduction to the Laboratory: A New Workshop in Partnership with the UW-Madison Center for Educational Opportunity”

A Nickel’s Worth of Free Advice: Biotech and the Law

This year’s participants in Emerging Techniques in Protein and Genetic Engineering, a two-credit graduate course offered in partnership with the Department of Oncology, UW-Madison, held July 17-21, 2017.

Today’s author extends thanks to Heather Gerard, Intellectual Property Manager, Promega Corporation for contributing her expertise to this post.

Students most often come to the BTC Institute with the primary goal of learning about molecular biology technologies. Our mission is to help them update their experimental tool-box, facilitating more capable studies of DNA, RNA and proteins back in their home laboratories.

But what else do we do? Well, we’re glad you asked.

Continue reading “A Nickel’s Worth of Free Advice: Biotech and the Law”

Next-Generation Genomics Education: Educating and Preparing the Next Generation

Students pursuing their interests wit h hands-on activities at BTC Institute.
Students pursuing their interests wit h hands-on activities at BTC Institute.

The BTC Institute has many partners in creating educational opportunities in the molecular biosciences. In recent years, we have worked with the Dane County School to Work Consortium (DCSWC) to create a unique, one-semester class aimed at giving high school Juniors and Seniors interested in scientific research and health careers a chance to explore how concepts they have been learning about in their biology and biotechnology classrooms are used in the laboratory.

To take it one step further, these laboratory experiences are tied to the Gates Foundation Grand Challenges in Global Health. The Challenges provide a framework to help students understand worldwide concerns, including ways in which biotechnology can be applied to generate solutions to these problems. Students are encouraged to place scientific challenges within social and socioeconomic contexts which, in turn, make some solutions more appealing than others. This holistic approach provides the “real world” milieu that is so sought after in academic endeavors. Continue reading “Next-Generation Genomics Education: Educating and Preparing the Next Generation”

Biotechnology Ice Breakers: A Few Conversation Starters

quiz pictureThe biotechnology industry is one of the most dynamic out there – in fact, it never stands still! For non-scientists this can be intimidating. For scientists, it can be challenging to explain what we do in ways that non-scientists can understand and appreciate.

Scientists have made great strides in improving our ability to use molecular processes to our advantage, from discovering the basics of how to isolate and manipulate DNA to gaining an understanding of how genes direct the creation of proteins in cells.  It’s clear that there is a lot we can contribute to the scientific literacy of the general public.

In this spirit, we’ve designed a short quiz for both non-scientists (you may learn something new) and scientists (you may find it useful for engaging in conversations with your non-scientist friends and family members).  Spoiler alert: answers are provided. Continue reading “Biotechnology Ice Breakers: A Few Conversation Starters”

Broaden Your Horizons While Pursuing Your Doctorate—You Will Be Glad You Did

For this posting, I had promised to include some commentary on ACTION.

image credit: ComiCONNMitch via Wikimedia Commons
image credit: ComiCONNMitch via Wikimedia Commons

What can someone pursuing a doctorate in the biosciences DO during that time to widen the possibilities of employment in the future? In general, the process of obtaining the doctorate has been criticized for taking too long and not doing enough to prepare students for what they will do when they graduate. Considering these criticisms, it seems wrong to create additional check-boxes on the student to-do list leading up to graduation. Therefore, these things are not in addition to what is already expected, but are instead the same things that are already happening re-focused. Continue reading “Broaden Your Horizons While Pursuing Your Doctorate—You Will Be Glad You Did”

Understanding Knowledge Transfer at the Doctoral Level – One Pathway to Better Career Development – An Introduction

Few studies have been conducted about knowledge transfer at the PhD level.
Few studies have been conducted about knowledge transfer at the PhD level.

Though my work is primarily in the area of biotechnology, my doctoral degree is in education. Over my next few posts, I thought that I would share some of the findings that came out of research I conducted for my dissertation.  It’s been over two years since graduation and much of this is still not published, though on my honor it’s in the works…I focused my study on understanding knowledge transfer at the doctoral level.  I was able to complete this work due to the generosity of many doctoral students, recent graduates and mentors across the country. This research was not funded in any way, but I believe it is of great importance given the socio-political context we are all functioning in as learners and professionals.  Also, many studies that are similar to the one I did are funded, with a great deal of money I might add. So, without further ado, let me start by introducing the concept of knowledge transfer and why developing knowledge transfer skills are important.

“Knowledge transfer” is a concept grounded in K-12 education and in a general sense refers to an individual’s ability to use knowledge gained in one context in another (similar or dissimilar) context. Continue reading “Understanding Knowledge Transfer at the Doctoral Level – One Pathway to Better Career Development – An Introduction”