The value of public funding for “basic” versus “applied” research has long been questioned. To address this debate, the authors of a recent report in Science performed a large-scale evaluation of the value of public investment in biomedical research. After analyzing the relationship between the U.S. National Institutes of Health (NIH) grants and private patents, they found that distinguishing research as basic or applied is not useful in determining the productivity of grant funding.
The $30 billion annual budget of the NIH makes it the largest source of life science funding in the world and provides a third of all US biomedical research and development. Although there has long been a strong argument for public investment in scientific research, attacks on the tangible benefits of this research persist. In particular, some opponents argue that “basic” research is too far removed from practical applications to be worthy of investment.
The definition of humanity is sacrosanct to many people. As science does, that line continues to blur. Stem cells have long been an ethical minefield for scientists to navigate for funding. Even something as common as an organ transplant was initially met with significant ethical concerns.
Most recently, the National Institutes of Health (NIH) has proposed changes to their policies controlling the funding for stem cell research creating human-animal chimeras. On the surface it may be hard for the general public to imagine that combining human and animal cells could result in anything other than mythical creatures of Homer’s Iliad. Human chimeras are much more common than one may believe, and the reason to allow studies on these models is to further our understanding of diseases and how to treat them. Continue reading “The Scientific Case for Studying Chimeras”
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