Keeping up with the pace of scientific discoveries being published each week can be difficult. Here I share a few scientific publications that piqued my interest over the past week:
Pollinators influence evolution of plant traits
Read the Nature Communications research article.
Calculus from Neanderthals reveal diet and probable self-medication
The calcified plaque on teeth of five Neanderthal skulls was scraped, PCR amplified and sequenced to examine what could be learned of diet, behavior and disease. One specimen was eliminated because the DNA did not amplify, one due to environmental contamination, leaving two specimens from Spain and one from Belgium that were used for analysis. The Belgian individual had rhinoceros, sheep and mushrooms caught in its teeth while the Spanish Neanderthals consumed mushrooms, pine nuts, forest moss, and poplar as well as plant fungus. The last two items were of interest because these sequences were found in the Neanderthal suffering from a dental abscess. Poplar contains the active ingredient in aspirin and the fungus was Penicillium from which the first antibiotic was derived. Researchers also compared the bacterial sequences of oral microbes across hominid species and sequenced a draft genome of the 48,000-year-old oral bacterium Methanobrevibacter oralis subsp. neandertalensis.
Read the research article in Nature.
The desiccation tolerance of water bears explained
Read a summary of the research in The Scientist (contains link to research article).
Blood type determined in 30 seconds using a paper-based assay
Matching blood type usually involves centrifuging blood samples to test both red blood cells and plasma, and takes about 30 minutes. However, a rapid test would be useful in emergencies while an alternate test for those without the funds for lab facilities would be beneficial. What about paper infused with dye that could show blood type in seconds, no centrifugation needed? In fact, researchers have developed a paper-based assay that uses microliter volumes of whole blood to determine blood type with a visual indicator. Using immobilized antibodies and a green dye, the blood will clump in the presence of an antibody that is recognized, turning the paper blue to show it has the marker for A (left side of chip) or B (right side of chip). Type AB will have both markers while type O has neither, turning the paper brown on both sides of the chip. Rare blood types and five Rhesus markers can also be analyzed using this paper-based chip assay, starting with a small sample of whole blood.
Read a summary of the research and watch a video of the paper assay chip in Science (contains link to research article).