I know that results in mice do not always translate to humans. I know that. I know that clinical trials can take years and that there are many hurdles between the first promising result in an animal model and the actual development of some form of treatment. Nevertheless I could not stifle a surge of hope when I heard about recent research suggesting that GM-CSF treatment reversed cognitive impairment and amyloid build-up in Alzheimer mice.
I have watched two family members succumb to Alzheimer’s disease. To me the news that something not only halted progression but actually reversed some of the cognitive impairment is huge. I know…its only in mice, but it’s the most promising news about this disease that I’ve heard in a while. And there’s more, the effective factor, GM-CSF, is already available in the drug Leukine, which is currently used to reduce risk of infection in cancer patients. Continue reading “Mice, Men and Alzheimer’s”