Life forms are often compared to machines, whether you are referring to a single cell or a complex organism. This concept is the basis for the International Genetically Engineered Machine (iGEM) Competition. Each year, high school and university students around the world assemble teams that create genetically engineered systems. In addition to the building work, teams document their process and progress through wikis that are assessed by judges at the end of the competition.
In order to synthesize these living machines, iGEM teams use standard biological parts called biobricks—each biobrick is a sequence of DNA encoding a particular biological function. Teams receive a kit of standard biobricks and work over the summer to build and test biological systems in living cells. These basic units are put together to make more complex parts which can then be grouped together to make “devices” that can function within living cells. Continue reading