Tracking the Progression of Plague Using Bioluminescence

Sequencing Yersinia pestis, the bacterium that caused the Black Plague in Europe during 1348–50, is an amazing accomplishment. Y. pestis infection still occurs sporatically and causes fatalities despite the Age of Antibiotics. Even with animal models, there are questions remaining about the progression of infection. Nham et al. used in vivo imaging to examine the course of infection in a mouse animal model using a bioluminescent clone of Y. pestis. Continue reading “Tracking the Progression of Plague Using Bioluminescence”